Studies on the Incidence and Inheritability of Spontaneous Tumors in Mice

Primary Spontaneous Tumors of the Testicle and Seminal Vesicle Ik Mice and Other Animals Xii, Studies in the Incidence and Inheritability of Spontaneous Tumors in Mice

Tumors of the testicle would seem to be uncommon in mice, for we have been unable to find even a single case reported in the literature, although they have been described in other species of lower animals. Thus, among 103 primary tumors observed by McCoy (1) among 100,000 rats killed in plague work, there was one described as an “angiosarcoma” of the testicle, without further details. Other ser...

Detection of Mouse Cytomegalovirus in Adenocarcinoma Bearing Razi/A Mice: Molecular and Pathological Studies

Despite a lot of research, the etiology and progression of breast cancer remain incompletely understood. Recently, human cytomegalovirus (HCMV) was reported as a risk factor for breast cancer. The aim of this study was to know whether breast cancer could be caused by cytomegalovirus or not? In this experiment seventeen samples of RAZI/A mice with spontaneous breast cancer were being gathered fr...

Primary Spontakeous Tumors in the Kidney and Adrenal of Mice Studies on Tre Incidence and Inheritability of Spontaneous Tumors in Mice

Primary tumors of the kidney occur not infrequently throughout the animal kingdom, and, in general, seem to exhibit the variations and peculiarities seen in human renal tumors. As an indication of the comparative pathology of renal tumors the following review of the literature is presented: Mouse: Few casm of primary renal tumors have been described among the great numbers of other tumors found...

The Inheritance Behavior of Cancer as a Simple Mendelian Recessive Studies in the Nature and Inheritability of Spontaneous Cancer in Mice Twenty-first Report

EFFECT OF IRON OVERLOAD ON 7, 12-DIMETHYLBENZ (A) ANTHRACENE-INDUCED SKIN TUMORIGENESIS

Iron overload is known to occur in the West European and American population due to the consumption of iron-rich diets. On the other hand, genetic disorders leading to iron overload are also known. Iron overload leads to increased peroxidation and disruptive disintegration of lipid-rich membranes, and predisposes humans for an enhanced risk of cancer induction. In experimental animals iron ...